With a week split between Vietnam and Cambodia, you can base yourself in Hanoi and Siem Reap and explore the cities' nearby natural and historical wonders on a highlights tour. Or, immerse yourself in the local way of life during a trip centered around a four-day Mekong River Cruise. Travelers looking for a mix of city, history, and nature tours will find Ho Chi Minh City and Siem Reap ideal bases, while those looking for some beach time should include Da Nang in their itinerary.

Itinerary #1: Northern Vietnam & Siem Reap Culture Escape

Enjoy a delightful sampling of Vietnam and Cambodia's rich culture and breathtaking landscapes on this northern Vietnam and Siem Reap escape crafted especially for first-time visitors. Starting in Hanoi, you'll learn about the city's highlights and cuisine alongside a guide and spend a day cycling and boating through Ninh Binh's rice paddies and dramatic limestone outcrops. You'll also set sail on an overnight cruise on Ha Long Bay before hopping over to Siem Reap to discover the wonders of Angkor Archaeological Park.

Board a sampan boat and sail through the widing rivers of the Ninh Binh province
Board a sampan boat and sail through the winding rivers of the Ninh Binh province
Day Highlights Overnight
Day 1 Arrive in Hanoi (Vietnam), City Tour & Water Puppet Show, Street Food Tour Hanoi
Day 2 Visit Hoa Lu & Ninh Binh, Cycling Tour & Tam Coc Boat Trip  Hanoi
Day 3 Transfer to Ha Long Bay, Athena Royal Cruise  Ha Long Bay
Day 4 Athena Royal Cruise, Transfer to Hanoi, Fly to Siem Reap (Cambodia) Siem Reap
Day 5 Angkor Temple Tour: Bayon Temple, Angkor Wat & Bakheng Hill Siem Reap
Day 6 Angkor Temple Tour: Banteay Srei, Ta Prohm & Ta Keo Siem Reap
Day 7 Khmer Village & Tonlé Sap Lake Tour, Depart  


Welcome to Vietnam! Your adventure begins in Hanoi, where you'll enlist the help of a guide to see the city's top sights, including the Presidential Palace and Hoan Kiem Lake, and sample flavor-packed street food dishes. Spend the following day discovering and exploring the Ninh Binh region, first on foot, then while cycling alongside rice paddies to Tam Coc, and lastly on a sampan boat ride through dramatic karst scenery. Next, transfer to Ha Long Harbor, board the luxurious Athena Royal, and delight in a memorable overnight cruise, which includes a cooking masterclass and time to kayak to hidden beaches.

After breakfast on the ship's deck and free time to relax or kayak, you'll head back to land on Day 4 and catch a flight to Siem Reap in Cambodia. The following two days are about exploring the impressive temples and ruins of the nearby Angkor Archaeological Park, starting with the ancient city of Angkor Thom and its Bayon Temple. You'll also wake early for a bucket-list-worthy sunrise from Angkor Wat and see Ta Prohm, whose ruins were featured in the "Tomb Raider" movies. On your final day, enjoy a pleasant cruise past the floating villages of Tonlé Sap before catching your onward flight. Learn more

Itinerary #2: Mekong River Cruise & Angkor Wat

Perfect for travelers looking to delve into life along the Mekong River, from remote floating villages to Cambodia's vibrant capital city of Phnom Penh, this quicker-paced journey features a four-night luxurious riverboat cruise. Between overnights onboard, you'll explore Cai Be by sampan, tour temples in Sa Dec, and visit a workshop in Hong Ngu. Then, round off your adventure with two days dedicated to exploring the UNESCO World Heritage Site of Angkor.

Experience life on the river in the Mekong Delta
Experience life on the river in the Mekong Delta
Day Highlights Overnight
Day 1 Arrive in Ho Chi Minh (Vietnam), Transfer to My Tho, Mekong Cruise Day 1 Cai Be
Day 2 Mekong Cruise Day 2: Rafting & Villages Tour Sa Dec
Day 3 Mekong Cruise Day 3: Farms, Villages & Weaving Workshops Hong Ngu
Day 4 Mekong Cruise Day 4: Free Day on the Mekong Phnom Penh
Day 5 Disembark & Tour Phnom Penh, Fly to Siem Reap (Cambodia), City Tour Siem Reap
Day 6 Day Trip to Angkor: Bayon Temple & Angkor Wat Siem Reap
Day 7 Sunrise at Angkor Wat & Temples, Depart Siem Reap  


Upon landing in Ho Chi Minh City, you'll be met by a driver and immediately be whisked south to My Tho. Here, you'll board the luxurious riverboat, the Mekong Navigator, and set off on a memorable four-night cruise along the Mekong Delta. Spend your first evening cruising to Cai Be while enjoying a Mekong-themed dinner onboard, then hop onto a sampan for a scenic ride past floating villages and coconut groves. Back on the Navigator, cruise to Sa Dec for a tour of local temples and the town market before continuing to the island village of Hong Ngu to learn about traditional weaving techniques. 

The final full day of your cruise has been purposely left open, allowing you to relax on the boat's sundeck or treat yourself at the onboard spa. Meanwhile, the ship will cross into Cambodia and dock in the capital, Phnom Penh. Disembark the following morning and wander among the city's highlights during a guided tour until it's time to catch a flight to Siem Reap. Dedicate the last two days of your trip to exploring the nearby UNESCO World Heritage Site of Angkor, home to the famous Angkor Wat and the mystical ruins of Ta Prohm and Ta Keo, before transferring to the airport in Siem Reap. Learn more

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Itinerary #3: Landmarks & Local Color in Vietnam & Cambodia

From zipping along the bustling streets of Ho Chi Minh City on a Vespa to gliding past floating villages on Southeast Asia's largest freshwater lake, this itinerary is all about experiencing the local way of life in Vietnam and Cambodia. Mixed throughout are visits to each country's renowned highlights, like the Cu Chi Tunnels and Angkor Wat. Foodies will also delight in evenings spent sampling street food and browsing lively markets. 

Tour Ho Chi Minh City by Vespa
Tour Ho Chi Minh City by Vespa
Day Highlights Overnight
Day 1 Arrive in Ho Chi Minh City (Vietnam), Self-Guided Tour Ho Chi Minh City
Day 2 Ho Chi Minh City Tour Ho Chi Minh City
Day 3 Day Trip to the Mekong Delta  Ho Chi Minh City
Day 4 Visit Cu Chi Tunnels, Vespa Food Tour Ho Chi Minh City
Day 5 Fly to Siem Reap (Cambodia), Tuk-Tuk Tour Siem Reap
Day 6 Day Trip to Angkor Siem Reap
Day 7 Visit Floating Villages, Depart  


Your journey begins with four days in the historic yet modern Ho Chi Minh City. Kickstart your stay with a self-guided walking tour, checking out iconic spots like the Ben Thanh Market and the Bitexco Tower. Then, enlist the help of a local guide the following day for a deeper introduction to the city's highlights, including the Reunification Palace and the War Remnants Museum, followed by an indulgent evening diving into the city's street food scene. Next, embark on a day trip to the Mekong Delta, where you'll board a boat, sail on the Ben Tre River, and tour a coconut candy workshop and honey farm.

With one more day based out of Ho Chi Minh City, you'll head out on another day trip, this time to the wartime famous Cu Chi Tunnels. Spend the evening zipping around the city on a Vespa, stopping to sample Vietnamese street food favorites before catching a flight to Siem Reap, Cambodia. After an evening exploring by tuk-tuk, you'll hop between the dazzling ruins of Angkor, including Angkor Thom, Bayon Temple, and Angkor Wat. Then, end your trip with a peaceful afternoon boating between floating villages on Tonlé Sap until it's time to transfer to the airport in Siem Reap. Learn more

Itinerary #4: Signatures of Vietnam & Cambodia: Da Nang, Hanoi & Siem Reap

Ideal for travelers eager to keep on the move and pack in the highlights of Vietnam and Cambodia, this weeklong adventure features two-night stays each in Da Nang, Hanoi, and Siem Reap. Between city tours and free time to explore at your leisure, you'll pack in a visit to the famous (and beautiful) Golden Bridge, float through Ninh Binh's limestone grottoes, and admire the legendary temples of Angkor. Then, round off your adventure by boating between Tonlé Sap's famous floating villages.

Detail of the Lady Buddha statue in Da Nang
Detail of the Lady Buddha statue in Da Nang
Day Highlights Overnight
Day 1 Arrive in Da Nang (Vietnam), Optional Beaches Da Nang
Day 2 Day Trip to the Golden Bridge Da Nang
Day 3 Fly to Hanoi, City Tour Hanoi
Day 4 Day Trip to Ninh Binh, Temples & Boat Rides Hanoi
Day 5 Fly to Siem Reap (Cambodia), Gateway to Angkor Siem Reap
Day 6 Day Trip to Angkor Temples Siem Reap
Day 7 Visit Banteay Srei & Floating Villages, Depart  


Your weeklong trip begins in Da Nang, an ideal spot to shrug off jet lag while strolling alongside the Han River and unwinding on My Khe, the city's main beach. Get straight to exploring the next morning with a day trip to the famous Golden Bridge on the agenda, followed by an evening sampling Da Nang's delectable street food. Then, board a flight bound for Hanoi on Day 3 and settle in for a two-night stay. Spend your first afternoon exploring the Ho Chi Minh Complex and the Museum of Ethnology alongside a guide, and wrap up the evening meandering through the historic Old Quarter.

Midway through your journey, delight in a break from the busy city while exploring the Ninh Binh region. Here, you'll visit the temples of Hoa Lu, float through limestone grottoes onboard a sampan boat, and enjoy panoramic views from Mua Cave. From Hanoi, catch a flight to Siem Reap, a resort town in northwest Cambodia. Settle in with a free evening to explore or relax, then dedicate the final two days of your adventure to wandering among Angkor's varied and impressively ornate temples, touring the artisan village of Preah Dak, and floating between wooden stilt houses set above Tonlé Sap. Learn more

Itinerary #5: Mekong Reflections: Journey Through Vietnam & Cambodia

Crafted for adventurers seeking a deeper dive into Vietnam and Cambodia's history, this weeklong itinerary showcases wartime relics, villages unchanged by time, and the wondrous ancient city of Angkor Thom. Starting in Ho Chi Minh City, you'll tour the Cu Chi Tunnels and War Remnants Museum and embark on a day trip to time-tested floating markets along the Mekong Delta. You'll also delight in a speedboat ride into Cambodia and spend a day roaming Angkor temples. 

Experience traditional life on the Mekong River
Experience traditional life on the Mekong River
Day Highlights Overnight
Day 1 Arrive in Ho Chi Minh City (Vietnam), War History Tour Ho Chi Minh City
Day 2 Day Trip to the Mekong Delta Ho Chi Minh City
Day 3 Transfer to Chau Doc via Cai Be Chau Doc
Day 4 Transfer to Phnom Penh (Cambodia) Phnom Penh
Day 5 Half-Day City Tour, Transfer to Siem Reap Siem Reap
Day 6 Day Trip to Angkor Temples Siem Reap
Day 7 Depart Siem Reap  


After arriving in Ho Chi Minh City and refreshing at your hotel, you'll dive into an immersive afternoon exploring the infamous Cu Chi Tunnels, touring the War Remnants Museum, and browsing Ben Thanh Market. Then, venture out of the city for a full-day tour of the famed Mekong Delta. Here, you'll take a boat ride through the area's floating markets and stroll along the orchard-lined backroads of Thoi Son Island. The following day sees you transferring to Chau Doc, stopping in Cai Be along the way to mingle with locals at one of the many floating markets and visit a "pop rice" (puffed rice) workshop.

From Chau Doc, settle in for a memorable five-hour speedboat ride along the Mekong River to Phnom Penh, the capital of Cambodia. Spend the evening strolling along the riverfront and through the Central Market independently, then enlist the help of an expert guide to discover the stories and secrets of the Royal Palace and Psar Toul Tom Pong. Transfer north to Siem Reap next and wrap up your adventure exploring Angkor Archaeological Park. Here, you'll roam Angkor Thom, an impressive royal city dating back to Cambodia's Angkor period, and its Bayon Temple and Terrace of Elephants. Learn more

More Great 1-Week Vietnam Itineraries

Looking for more inspiration for your trip to Vietnam? Check out these other one-week Vietnam itineraries, with outdoor adventures, cultural trips, and best-of tours to hit the highlights.

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Map of 1 Week in Vietnam & Cambodia - 5 Unique Itinerary Ideas
Map of 1 Week in Vietnam & Cambodia - 5 Unique Itinerary Ideas