2 Weeks in Argentina & Chile - 5 Unique Itinerary Ideas

Itinerary #1: Natural Wonders of Argentina & Chile: Waterfalls, Glaciers & National Parks

Discover Argentina and Chile's natural wonders and vibrant cities on this two-week trip, with highlights including Iguazú National Park, Perito Moreno Glacier, Torres del Paine National Park, and time in capital cities Buenos Aires and Santiago. This itinerary is perfect for first-time visitors and nature lovers, as it offers the chance to hike, boat, and 4WD under towering mountains and next to magnificent glaciers.

Welcome to Argentina! Your adventure begins with three nights in Buenos Aires, the capital city and the perfect place to get to know the country's culture and history. Start on a guided tour of the city, spend a day on a nearby working estancia (ranch), and end your stay attending a tango show in the neighborhood of Monserrat. Next, board a flight bound for Puerto Iguazú and continue to Iguazú Falls, where you'll delight in two thrilling days exploring the national park by train and on foot. Then, on Day 6, it's back to the airport to catch your flight to El Calafate, the gateway to Los Glaciares National Park.

After spending your first evening in El Calafate at the Glaciarium, you'll delight in an up-close visit to Perito Moreno Glacier. Venture next to Puerto Natales (Chile) and enjoy a leisurely evening before heading into Torres del Paine National Park. Make the most of your two days in the park by joining a full-day guided tour and using your free day to trek to Lago Grey, ice hike on Grey Glacier, or embark on a 4WD vehicle sightseeing tour. Then, fly to Santiago and devote your last days in Chile, tasting your way around the city and joining a wine tour in the Casablanca Valley. Learn more

Itinerary #2: Explore Northern Argentina & Chile

Crafted for those seeking a perfect blend of cultural experiences and outdoor adventures, this two-week trip in Northern Argentina and Chile features the vibrant cities of Santiago and Buenos Aires, Rainbow Valley in the Atacama Desert, and whitewater rafting in Salta. Other highlights include a live tango show in Buenos Aires, a panoramic city tour of Santiago, and a full-day excursion to Cafayate.

Your two-week trip begins in Santiago, shrugging off jet lag while visiting main attractions like La Moneda Presidential Palace and the Plaza de Armas and exploring the coastal areas of Valparaíso and Viña del Mar. Then, catch a flight to Calama and transfer to San Pedro de Atacama. Spend the following three days taking in the Atacama Desert's striking landscapes, including Rainbow Valley, the Tatio Geothermal Field, Los Flamencos National Reserve, and Piedras Rojas. Before bidding farewell to Chile, enjoy your final day in the region soaking in the salty waters of Laguna Piedra.

Next on your agenda is a bus ride to Salta in Argentina, a town famous for its breathtaking scenery and rich Indigenous culture. During your stay, you'll drive through the Lerma Valley to Cafayate for a winery visit, admire Seven Colors Hill, and thrill to a whitewater rafting adventure on the Río Juramento. Then, head back to the airport on Day 11 for a flight to Buenos Aires, and spend your last four days enjoying a tango show, sampling Palermo district's mouthwatering cuisine, and joining a private sailing trip in the Paraná Delta. Learn more

Itinerary #3: Outdoor Adventures & Cultural Exploration in Argentina & Chile

Perfect for outdoor enthusiasts looking to mix in some city time, this two-week trip includes an exhilarating trek in the Tierra del Fuego National Park, an intimate encounter with the Perito Moreno Glacier, and two days exploring Torres del Paine National Park. You'll also start your adventure in Buenos Aires and end your stay in Santiago, allowing you to include a live tango performance and city tours.

After landing in Buenos Aires and settling into your hotel, you'll kick off your adventure by joining a live tango show and dinner in Monserrat. Over the following two days, you'll continue your cultural exploration by going on a guided city walk and visiting an estancia near San Antonio de Areco. Then, fly to Ushuaia, the world's southernmost city, for three days of exploring Tierra del Fuego National Park and its surroundings. Take the End of the World Train, cruise along the Beagle Channel, and hike to the dramatic Laguna Esmeralda before flying to El Calafate.

You will spend two eventful days in El Calafate, journeying along the shores of Lago Argentino by 4WD and admiring Perito Moreno Glacier on foot and by boat. Next, continue south to Puerto Natales, the gateway to Torres del Paine National Park, and check out its jaw-dropping landscapes, including the Salto Grande waterfall, Lago Nordenskjöld, and Cañadón Macho, an area known for its population of condors and guanacos. Then, you'll return to city life, this time in Santiago, where you'll visit the nearby coastal towns of Valparaíso and Viña del Mar before catching your flight home. Learn more

Itinerary #4: Discover Cities, Waterfalls & Lakes in Argentina & Chile

Complete with three flights and a boat and bus transfer, you'll experience the best of Central and Northern Argentina and Chile on this active getaway. Ideal for those who want to spend uninterrupted time in nature, you'll embark on hikes near Bariloche and on Osorno volcano and delight in scenic cruises on the Río Iguazú and the glacial lake of Nahuel Huapi. Plus, you'll enjoy city tours and further cultural experiences with time in Buenos Aires and Santiago.

Start your adventure in colorful Buenos Aires, getting your bearings in Argentina while attending a live tango show, touring the grand Plaza de Mayo and waterfront La Boca, and sampling the local cuisine in the Palermo district. You'll next board a plane bound for Puerto Iguazú, home to the famous Iguazú Falls, and settle in for three days of sightseeing. Begin with a memorable sunset catamaran ride, ponder the thundering Garganta del Diablo (Devil's Throat) falls, and raft toward the San Martín and Tres Musqueteros waterfalls. Then, it's off to Bariloche in the Lake District, reachable by a four-hour flight.

Using Bariloche as your base, you'll enjoy two days of trekking the Circuito Chico and sailing across the glacial lake of Nahuel Huapi before transferring to Puerto Varas by boat and bus. Lace up your hiking boots and trek on the slopes of Osorno volcano and the Paso Desolación (Desolation Path), and in between, sample Bavarian-style sausages in the German-influenced town of Llanquihue. On Day 12, you'll catch a flight to Santiago, where you'll spend your final days admiring city highlights on a guided tour and strolling the streets of Valparaíso and Viña del Mar. Learn more

Itinerary #5: Chile & Argentina Fjord Cruise & Desert Adventure

Split your time between cruising Chile and Argentina's southern fjords, exploring Torres del Paine National Park, and touring San Pedro de Atacama's remote and otherworldly landscapes on this two-week adventure. Crafted for those looking to escape the crowds and get off the main tourist path, you'll hike to glaciers reachable only by boat, kayak the quiet waters of Eberhard Fjord, and admire flocks of flamingoes in the Los Flamencos National Reserve.

Your trip begins in the world's southernmost city, Ushuaia. Enjoy a leisurely afternoon strolling the city's waterfront and getting ready to embark on a five-day fjord and glacier cruise the following evening. Start by traversing the Beagle Channel and crossing Nassau Bay, then head ashore to explore Cape Horn National Park and Wulaia Bay. Your cruise continues around the glaciers at the western end of Tierra del Fuego and to Garibaldi Glacier, where you'll stop for a hike before sailing through to Agostini Sound. After visiting Isla Magdalena to admire the resident penguins, you'll disembark in Punta Arenas.

Your next destination is Puerto Natales, where you'll tour Torres del Paine National Park and kayak the turquoise waters of Eberhard Fjord before flying to Santiago. After spending time in remote landscapes, the buzzing capital city will feel extra exciting, especially with a city tour and private dining experience on the agenda. However, it's back to nature on Day 11, this time to Calama, located in Chile's far north. Continue to San Pedro de Atacama, the gateway to the Atacama Desert, and spend your final days exploring salt flats and lagoons, the Tatio Geysers, and the Valley of the Moon. Learn more

More Great 2-Week Argentina Itineraries

Looking for more inspiration for your trip to Argentina? Check out these other two-week Argentina itineraries, with outdoor adventures, cultural trips, and best-of tours to hit the highlights.