Italy 10-Day Self-Drive Tours & Itineraries

Explore 6 self-drive trips designed by local kimkim specialists to get ideas for your trip to Italy.

Embark on an adventure through Italy with these 10-day self-drive itineraries, each offering a distinct taste of the country's rich heritage, gorgeous landscapes, and culinary delights. If you're after an upscale experience, consider something like this luxury drive, where you'll journey from Milan's elegant streets down to the history-soaked plazas of Naples, with wine tastings and art viewings in between. For families, you might opt for a trip similar to this Northern Italy family road trip that includes Florence, Lake Como, and Lake Garda, featuring child-friendly stops. If you're drawn to Sicily, you'll likely prefer this Sicilian highlights route, where you'll see Palermo's architecture, Catania's markets, medieval towns, and beautiful coastlines.  

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Visit the hilltop city of Agrigento
Map of Sicily Highlights Self-Drive Tour - 10 Days
Sicily Highlights Self-Drive Tour - 10 Days

This 10-day itinerary features a perfect mix of culture, history, adventure, and relaxation. Explore ancient Greek and Roman cities, medieval hilltop towns dotted with ornate baroque buildings, and coastal ramparts. Begin in Sicily's regional capital of Palermo and drive your way around the Italian island to end in Catania. You'll visit stunning landscapes, like Trapani's historic salt pans, sip fortified wine in charming Marsala,  and dine on fresh seafood in sophisticated Taormina.

Florence from San Miniato al Monte Church
Map of Northern Italy Family Road Trip: Florence, Chianti, Italian Riviera, Lake Como & Lake Garda - 10 Days
Northern Italy Family Road Trip: Florence, Chianti, Italian Riviera, Lake Como & Lake Garda - 10 Days

Wheel your way through northern Italy on this road trip with stops that school-aged children and parents can enjoy, with timing adjustable to your own preferences. You'll start amid the Renaissance influences of Florence, then set out into the Tuscan countryside and Chianti Valley on winding olive- and vineyard-lined roads. From there, head to the coast to wander the beaches of the Italian Riviera and then up to Lake Como to explore its luxurious shores. Wrap up your Italian sojourn on the playful shores of Lake Garda before you return to Florence.

Learn about the height of the Roman Empire from your private guide
Map of Rome, Assisi & Florence - 10 Days
Rome, Assisi & Florence - 10 Days

If you have 10 days to spend in Italy, this tour blends two world-class cities and a road trip through the countryside for a well-rounded adventure. Start in Rome to see the Vatican and learn about the height of the Roman Empire with local guides. Then pick up a rental car and make your way to the hilly Umbria region for medieval towns, like UNESCO-listed Assisi, plus wineries and olive groves. Finish in Florence for Renaissance culture and a cooking class, where you'll learn recipes to take home.

Turin's Piazza Castello
Luxury Driving in Italy: Milan, Turin, Florence, Viterbo & Naples - 10 days

Experience Italy from north to south in all its glory with this diverse 10-day self-drive itinerary. Tour Milan's magnificent gothic Duomo, sample Piedmont cuisine in Turin, visit the wine country of the Langhe region, and soak up the Renaissance atmosphere of Florence. Your journey ends in vibrant Naples, where you'll step back in time with a tour of ancient Pompeii.

Siena is your first stop on this Tuscan road trip
Map of Explore Tuscany: Florence, Siena & Montepulciano - 10 Days
Explore Tuscany: Florence, Siena & Montepulciano - 10 Days

This sophisticated 10-day trip is ideal for travelers looking to experience art, culture, food, and wine—all things that make Tuscany one of Italy's most sought-after regions. Start in Florence, the birthplace of Renaissance art and architecture, to experience the city's rich history and walkable center. Then begin a self-guided road trip around Tuscany, visiting UNESCO-listed monuments, picturesque hill towns, and notable vineyards, including a memorable sit-down lunch and wine pairing in Montepulciano.

Head to Ortygia's Fonte Aretusa, a natural spring
Map of Sicily Highlights Self-Drive Tour with Aeolian Islands - 10 Days
Sicily Highlights Self-Drive Tour with Aeolian Islands - 10 Days

Discover the highlights of Sicily with this 10-day loop of the island, featuring three nights on two of the Aeolian Islands as well as time spent in Palermo, the regional capital, and historic Syracuse. You'll witness Stromboli's spectacular pyrotechnic display of red and orange lava, take a passeggiata along Cefalù's seaside promenade, and enjoy traditional Sicilian fare in a rustic trattoria in Syracuse's historic core. Explore historic Norman castles, ancient Greek temples, and Roman amphitheaters, and enjoy the impressive baroque architecture of lively Catania.

Other durations: 7 days · 8 days · 9 days · 10 days · 11 days · 12 days · 13 days · 14 days · 15 days · 16 days