Panama 10-Day Tours & Itineraries

Explore 9 trips designed by local kimkim specialists to get ideas for your trip to Panama.

Explore Panama with these 10-day itineraries, each designed to give you an immersive experience. For those wanting a mix of island retreats, highland coffee tastings, and historical exploration, consider a trip like this Panama Adventure, where you'll visit secluded Isla Palenque and explore the lively streets of Panama City. If you'd like a journey that includes night hikes in rainforests, sailing to uninhabited islands, and tasting local delicacies through an eco-conscious lens, an itinerary like this Panama adventure might be the way to go. You might also enjoy something similar to this nature and beaches itinerary, where you'll take boat rides of the Panama Canal and visit remote Naso tribes. 

See our itineraries below or read our guide to the best 10-day trips in Panama.

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A waterfall near the village of Boquete
Map of Panama Multi-Sport Adventure - 11 Days
Panama Multi-Sport Adventure - 11 Days

Get ready for an active trip to an undiscovered region of Panama that combines beautiful landscapes, exuberant nature, and pleasant weather. On this 11-day multi-sport itinerary, you'll fly through a cloud forest, raft along a river, and trek up a volcano where you can witness two oceans from above before camping under the stars—an unforgettable experience!

The Pearl Islands
Panama Island Tour: Panama City, Pearl Islands & Bocas del Toro - 10 Days

This 10-day tour of Panama takes you from the city to the islands. Visit the world-famous Panama Canal and UNESCO World Heritage Site of Casco Viejo in Panama City. Then, venture to the Pearl Islands for some whale watching, hiking, and beach relaxation. Return to the city for more exploration, and head to Bocas del Toro for a few more relaxing free days by the beach enjoying nature walks and the surrounding waters. Spend a bit more time in Panama City to close out your visit.

Whale in the Pacific Ocean
Map of Panama's Pacific Coast: Panama City, Playa Reina, & Santa Catalina - 10 Days
Panama's Pacific Coast: Panama City, Playa Reina, & Santa Catalina - 10 Days

This 10-day trip to Panama’s Pacific Coast is the perfect mix of exploration and relaxation. Begin in Panama City, where you’ll tour the iconic Panama Canal, Casco Viejo, and take a day trip to visit the indigenous Emberá. Then, rent a car and drive to the beach—you’ll stay in Playa Reina for two nights, where you can observe turtles nesting and hatching. Next, enjoy some surfing and downtime in Santa Catalina, followed by a whale-watching excursion, before you return to Panama City.

Panama's Pacific Coast
Map of Insider's Panama:  Isla Palenque, Boquete, Portobelo & Panama City - 10 Days
Insider's Panama: Isla Palenque, Boquete, Portobelo & Panama City - 10 Days

Discover the quieter corners of Panama on this 10-day journey between cities, mountains, and coasts. Escape to an island paradise in the Gulf of Chiriquí, explore the lush coffee region of Boquete, and immerse yourself in Caribbean culture in the laid-back fishing village of Portobelo. Your getaway ends in the capital of Panama City, where you'll tour the historic Casco Viejo and watch ships transit the famous Panama Canal.

Panama not only has pristine beaches but rugged mountains as well
Map of Off-the-Beaten-Path Panama - 10 Days
Off-the-Beaten-Path Panama - 10 Days

Nature enthusiasts will enjoy this 10-day journey through Panama, exploring national parks, secluded villages, and Caribbean islands. Starting in Panama City, you'll venture to three national parks for luscious rainforest hikes and dinners with a view. Then, cruise to the southern Golfo de Chiriquí to island hop via sailboat before visiting the mountainous Boquete region for coffee and honey tastings. Conclude your trip on Bocas del Toro's Caribbean islands to snorkel off the white sandy coasts.

Take in the epic views of Panama from mountain to coast
Map of Panama Road Trip: City to Mountains to Beach - 10 Days
Panama Road Trip: City to Mountains to Beach - 10 Days

Road trip your way through the best of Panama on this intrepid 10-day tour. Arrive in Panama City, where you'll taste the capital's best flavors and cruise down the Panama Canal. Get behind the wheel and head to the mountainous town of Valle de Antón next for lush rainforest, spectacular wildlife, local culture, and outdoor adventure. Then, it's on to the Pacific coast to explore the beaches, islands, mangrove forests, and coral reefs around Playa Venao and Coiba National Park.

Spend three nights in the Bocas del Toro islands for snorkeling, boat trips, and beach time
Map of Panama City, Cloud Forest & Island Adventure - 10 Days
Panama City, Cloud Forest & Island Adventure - 10 Days

Dive into the best of Panama with this 10-day tour that hops between the busy capital, mountain cloud forests, and Caribbean islands. Explore Panama City's historic streets and kayak down the famous Panama Canal, then head to the peaceful highland town of Volcán to hike in wildlife-rich national forests and watch the sunset from the country's highest volcano. End in the idyllic Bocas del Toros archipelago to snorkel in clear waters, visit an island of monkeys, and relax on pristine beaches.

Hop between islands to spot birds and wildlife around Isla Bastimentos
Map of Nature & Beaches in Panama City & Bocas del Toro - 10 Days
Nature & Beaches in Panama City & Bocas del Toro - 10 Days

Bird-watchers and beach lovers can indulge their senses on this 10-day adventure through Panama's rainforests and Caribbean islands. Beginning in Panama City, you'll explore the historical Casco Antiguo and the Panama Canal before venturing to the tropical Bocas del Toro. Next, meet remote tribes in La Amistad International Park and then learn how cacao is cultivated from bean to chocolate. From snorkeling among coral reefs to observing seabirds, there's no shortage of natural wonders to behold.

Sail your way through the tropical paradise of the San Blas Islands, Panama
Map of Panama Hiking & Sailing Adventure - 10 Days
Panama Hiking & Sailing Adventure - 10 Days

This adventure of two parts begins with a journey deep into Chagres National Park, where you'll hit the trail for a multiday hike along the Camino Real. Cross dense jungle, skirt winding rivers, and spot diverse wildlife before finishing among the historic forts and Caribbean coasts of Portobelo. Then it's time to switch gears and put your feet up as you head to the tropical San Blas archipelago for a four-day sailing tour of white beaches, palm trees, and an up-close look at the local Guna culture.

Other durations: 5 days · 7 days · 8 days · 10 days