Located in the beautiful Provence region of France, Avignon and Arles are 20 miles (33 km) apart. By train, it's a quick 20-minute ride, while driving will take you about an hour.
If you want to take the time to fully explore both cities, this 9-day self-driving tour from Paris takes you to Aix-en-Provence, the Roman ruins of Arles, and the Châteauneuf-du-Pape vineyards on your way to Avignon.
If you'd rather spend less time in Arles, this 8-day cycling itinerary and this 7-day itinerary inspired by the Obamas' recent trip to the region both include a quick day trip to the city that famously inspired Van Gogh.
Duration: 20 minutes
This is the fastest option to visit Arles from Avignon. The Avignon Centre Train Station is only half a mile (1km) away from the city center, and there are many trains to Arles each day from 5 a.m. to 9 p.m.
The Arles train station is also very close to the city center (less than 0.5 miles/1 km) and you can take a free shuttle bus, private transfer or even walk to your destination.
By Rental Car or Private Transfer
Duration: 50 minutes
Renting a car gives you more freedom to explore the small villages of Provence and step a bit off the beaten path. You'll take the N1007 and D570N, and the road is clearly marked. Private transfers are also available if you prefer not to drive.
Options to visit en-route include Les Baux-de-Provence, a stunning fortified medieval village about 30 minutes away from Arles and Saint-Rémy-de-Provence, a quintessential Provençal village about halfway between the two cities.