Bariloche and Chacras de Coria, a small town outside of Mendoza known for its wineries, sit about 772 miles (1,220 km) apart on Argentina's western border. To get from one to the other, a plane ride is your best bet, though the options are relatively limited from Bariloche's small airport. Booking a rental car and taking about 15 hours to explore the cities and landscapes between these two places may be an enjoyable option.
Once you arrive in Chacras de Coria, this Ultimate Guide to Mendoza could provide inspiration for your time in town and the surrounding areas.
Duration: 3 hours, 25 minutes, depending on connections
The quickest way to get from Bariloche to Chacras de Coria is by plane from the San Carlos de Bariloche Airport (BRC) to the Mendoza International Airport (MDZ), though direct flights are rare.
Aerolineas Argentinas, Latam, and Norweigan Air offer daily flights with layovers in Córdoba International Aiport (COR) in Córdoba and Aeroparque (AEP) in Buenos Aires. Even with layovers, this is still your most efficient option. JetSmart offers much shorter direct flights (that take about one hour and 40 minutes), but its schedule is sporadic—it only offers these flights on Wednesdays and Saturdays.
From the airport, it's a 15 to 20-minute drive to Chacras de Coria. You can take a private transfer, rental car, or taxi to cover the short last leg of the trip.
By Rental Car or Private Transfer
Duration: 15 hours, more with an overnight stop
For an option that allows you to set your own schedule, consider taking a rental car between Bariloche and Chacras de Coria. The fastest route is via Argentina's RN327, which crosses through northern Patagonia before taking you into Mendoza Province. Consider stopping in Neuquen, a city famous for its dinosaur fossils, for a break.
For a chance to do even more sight-seeing on your way north, consider diverting into Chile and following Panamericana Sur/Ruta 5. The ride will take longer, nearly 19 hours, but along the way you can stop in cities like Osorno and Santiago de Chile which lie along Chile's longest highway.