With 10 days in the Galápagos, you can visit multiple islands and still enjoy a couple of days on mainland Ecuador. For ultimate luxury, board a superyacht and sail between nine spectacular islands. Alternatively, choose a shorter cruise to allow more time for exploring Quito and Guayaquil. If you prefer top-notch resorts, a land-based trip combining adventurous excursions and relaxing boat tours is ideal, or consider a detour to the lush Ecuadorian Amazon for incredible wildlife encounters.

Itinerary #1: Galápagos Grandeur: Explore the Archipelago by Luxury Yacht

Indulge in endless days of sun, sea, and beautiful coastlines on this luxury Galápagos cruise, designed for discerning travelers with an affinity for wildlife. Onboard the Agua Mare superyacht, cruise between nine islands and islets, and disembark to hike, snorkel, beach hop, and witness fascinating bird and marine life. Plus, with nights in Quito bookending your time in the Galápagos archipelago, you'll sneak in a visit to the Museo Casa de la Cultural and refresh in style at the premier EB Hotel by Eurobuilding.

All aboard your Galápagos super yacht! (photo courtesy of Aqua Mare)
All aboard your Galápagos super yacht! (Photo courtesy of Aqua Mare)
Day Highlights Overnight
Day 1 Arrive in Quito, Optional Activities Quito
Day 2 Fly to the Galápagos, Visit Highland Ranch & Board Ship Cruise Ship
Day 3 Cruise to Isla Floreana: Cormorant Point & Post Office Bay Cruise Ship
Day 4 Cruise to Isla Isabela: Punta Moreno & Urbina Bay Cruise Ship
Day 5 Cruise to Isla Fernandina: Espinoza Point & Tagus Cove Cruise Ship
Day 6 Cruise to Isla Santiago: Egas Port, Espumilla Beach & Buccaneer Cove Cruise Ship
Day 7 Cruise to Isla Rábida & Black Turtle Cove Cruise Ship
Day 8 Cruise to Isla Seymour Norte & Mosquera Islet Cruise Ship
Day 9 Cruise by Daphne Major, Fly to Quito & Farewell Dinner  Quito
Day 10 Visit Cultural Museum, Depart Quito  


Welcome to Ecuador! Your luxury escape begins in Quito, but after an overnight at the well-appointed EB Hotel by Eurobuilding, you'll return to the airport to catch a flight to the Galápagos. Upon landing, transfer to Puerto Ayora, where the premier Agua Mare superyacht welcomes you onboard for a six-night stay. Disembark on nine different islands throughout your cruise, each brimming with fascinating wildlife and coastal landscapes. Kick things off with a day of beach hopping and sea lion spotting on Isla Floreana, then explore Isla Isabela's volcanic landscapes and coastal plains. 

Your next cruising destination is Isla Fernandina, home to colonies of marine iguanas and nesting flightless cormorants, followed by Isla Santiago, the best place in the archipelago to observe Galápagos fur seals. Afterward, relax on the red-sand beaches of Isla Rábida and explore the beautiful mangrove forests at Black Turtle Cove. Isla Seymour Norte and the islet of Mosquera are two more destinations you'll disembark at, the first to spot blue-footed boobies and the latter featuring a sandbar brimming with shorebirds. Lastly, snorkel off the coast of Daphne Major before flying back to Quito. Learn more

Itinerary #2: Ultimate Luxury Exploration of the Galápagos

Discover uninhabited islands, underwater geological formations, and beaches teeming with extraordinary wildlife on this activity-packed adventure. Perfect for those seeking a land-based trip, you'll spend nights at upscale accommodations and your days hiking, biking, snorkeling, and cruising. Highlights include a guided e-bike excursion around Isla Santa Cruz, a hike up the rugged Sierra Negra volcano, and a snorkeling trip to the renowned Kicker Rock—all of which offer superb opportunities to witness rare birds and marine animals.

Combine the stunning natural wonders of the Galápagos with stays in 5-star accommodation (photo courtesy of Hotel Indigo, Galápagos)
Combine the wonders of the Galápagos with 5-star accommodations (photo courtesy of Hotel Indigo, Galápagos)
Day Highlights Overnight
Day 1 Arrive in Quito, Optional Activities Quito
Day 2 Fly to the Galápagos, Visit Charles Darwin Research Station Isla Santa Cruz
Day 3 Isla Santa Cruz E-Bike Tour Isla Santa Cruz
Day 4 Galápagos Hidden Gems Cruise Isla Santa Cruz
Day 5 Fly to Isla Isabela, Visit Tintoreras Islet Isla Isabela
Day 6 Hike to Volcano Sierra Negra Isla Isabela
Day 7 Fly to Isla San Cristóbal, Visit Tijeretas Hill & La Lobería Isla San Cristóbal
Day 8 Day Trip to Kicker Rock & Snorkeling Isla San Cristóbal
Day 9 Visit El Junco Lagoon, Tortoise Center & Puerto Chino Beach Isla San Cristóbal
Day 10 Massage at Hotel Indigo, Fly to Quito, Depart  


After arriving in Quito and taking the evening to relax at the EB Hotel by Eurobuilding, you'll be refreshed and ready to discover the magnificent wonders of the Galápagos archipelago. Your first destination is Isla Santa Cruz, and with a visit to the Charles Darwin Research Center and a guided e-bike tour on the agenda, you'll quickly become acquainted with the archipelago's wildlife. Additionally, experience the unspoiled beauty of nearby uninhabited islands during a private cruise before jetting to Isla Isabela. Here, the luxury Iguana Crossing hotel welcomes your arrival for two luxe overnights.

Kick off your stay on Isla Isabela with an afternoon of boating and hiking, followed by a memorable trek on the Sierra Negra volcano. Another flight then sees you to Isla San Cristóbal, and after dropping your bags at the chic Hotel Indigo Galápagos, spend the rest of the day hiking up Las Tijeretas Hill and admiring sea lions at La Lobería. It's back out on the water on Day 8, this time onboard a speedboat destined for Kicker Rock. Lastly, visit a giant tortoise breeding center and treat yourself to a well-deserved massage before catching your onward flight. Learn more

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Itinerary #3: Luxury Galápagos Cruise & Highlights of Cuenca & Quito

Ideal for luxury travelers looking to experience both the hidden corners of the Galápagos and the enchanting towns of mainland Ecuador, this far-reaching Ecuadorian itinerary combines a six-day cruise with time in Guayaquil, Cuenca, and Quito. While based onboard the marvelous M/C Endemic, sail between volcanic islands and rocky islets, disembarking for a mix of hiking, sightseeing, and wildlife-watching excursions. Then, join up with expert guides on the mainland to admire stunning cathedrals, visit the former home of a famous Ecuadorian artist, and take in the massive Monument to the Equator.

Explore the islands of the Galápagos by day, and relax onboard your luxury cruiser at night (photo courtesy of M/C Endemic )
Explore Galápagos islands by day and relax onboard your luxury cruiser at night (photo courtesy of M/C Endemic )
Day Highlights Overnight
Day 1 Arrive in Guayaquil, Half-Day City Tour Guayaquil
Day 2 Fly to the Galápagos, Transfer to Cruise Ship Cruise Ship
Day 3 Cruise to Isla Isabela: Sierra Negra Volcano & Tortoise Breeding Center Cruise Ship
Day 4 Explore Isla Isabela: Elizabeth Bay & Urbina Bay Cruise Ship
Day 5 Visit Tagus Cove, Cruise to Isla Fernandina & Espinoza Point Cruise Ship
Day 6 Cruise to Isla Santiago: Buccaneer Cove & Isla Rábida  Cruise Ship
Day 7 Visit Mosquera Islet, Disembark Cruise, Fly to Guayaquil Guayaquil
Day 8 Transfer to Cuenca, City Tour Cuenca
Day 9 Fly to Quito, Art Museum Tour Quito
Day 10 Visit Mitad del Mundo & Agave Museum, Depart Quito  


With its charming waterfront and modern luxuries, Guayaquil is the perfect place to shrug off jet lag in style, which is exactly what you'll do while based at the 5-star Hotel del Parque. The next day, you're off to the Galápagos to begin your five-day cruise onboard the opulent M/C Endemic. Throughout, when you're not relaxing in your well-appointed stateroom, you'll have ample opportunity to disembark for activities catered to your liking. From hiking lunar-like landscapes to watching curious blue-footed boobies, each promises to introduce you to the mind-blowing biodiversity of the archipelago.

Additionally, while based onboard the M/C Endemic, cruise to Isla Rábida to admire its cactus groves and to Mosquera Islet in hopes of encountering the yellow-crowned heron. Then, after disembarking for the final time, bid farewell to the islands and fly to Guayaquil. Spend a night here before transferring inland to Cuenca, known as the "Athens of Ecuador," where you'll join a guide to learn about the city's cathedrals. Your final destination is Quito, and with a full day here, you'll have time to ponder artworks at Casa Museo Guayasamín and straddle the equator at Mitad del Mundo. Learn more

Itinerary #4: Galápagos Safari Camp Luxury Adventure

Fully surround yourself with the natural wonders of the Galápagos Islands on this leisurely-paced 10-day journey. While staying at the delightfully exclusive Galápagos Safari Camp and the Scalesia Galápagos Lodge, you'll find plenty of time to unwind in style between activities curated to your interests. Dedicate two days to cruising between uninhabited islands, exploring the white sands of Garrapatero Beach and trekking to the crater rim of the Sierra Negra volcano. Then, jet to Quito and spend your final days sipping cocktails and meandering through the city's colonial center.

Wake up to the sounds of local wildlife at your luxury safari camp (photo courtesy of Galápagos Safari Camp)
Wake up to the sounds of local wildlife at your luxury safari camp (photo courtesy of Galápagos Safari Camp)
Day Highlights Overnight
Day 1 Arrive in Quito, Mitad del Mundo & Agave Museum Quito
Day 2 Fly to Galápagos, Transfer to Safari Camp, Visit Tortoise Reserve Isla Santa Cruz
Day 3 Galápagos Hidden Gems Cruise (Day 1) Isla Santa Cruz
Day 4 Galápagos Hidden Gems Cruise (Day 2) Isla Santa Cruz
Day 5 Nature Reserve, Beaches & Kayaking Isla Santa Cruz
Day 6 Fly to Isla Isabela, Explore the Wetlands Isla Isabela
Day 7 Day Trip to Sierra Negra & Las Tintoreras Isla Isabela
Day 8 Fly to Quito, Evening Cocktail Class Quito
Day 9 Tour Quito's UNESCO-listed Historic Center  Quito
Day 10 Visit Botanical Gardens, Depart Quito  


Start your lavish escape in Quito, admiring the grand Monument to the Equator and savoring fine spirits at the Agave Museum. From there, fly to the Galápagos and transfer to the esteemed Galápagos Safari Camp on Isla Santa Cruz, your base for the next four nights. After unpacking, venture to volcanic sinkholes brimming with unique wildlife with a naturalist guide, then embark on back-to-back private boat trips to secluded islands. Later, wrap up your visit to Isla Santa Cruz by exploring a private nature reserve and lounging on the beautiful white sands of Garrapatero Beach.

The second half of your getaway features the luxurious Scalesia Galápagos Lodge on Isla Isabela, and over a two-day stay, you'll have plenty of time to explore the property's expansive native forest. While here, you'll also hike around the mangroves of Los Humedales, conquer a trek on the Sierra Negra volcano, and cruise to Tintoreras Islet. Afterward, jet back to Quito and wrap up your trip with a healthy dose of culture. First, head to a local bar for a special cocktail-making class, then join up with a local guide for a private walking tour before squeezing in a visit to the city's botanical gardens. Learn more

Itinerary #5: Luxury Adventure in the Ecuadorian Amazon & the Galápagos

From a spectacular lodge tucked deep in the Amazon and the beachfront Golden Bay Galápagos boutique hotel to a decadent spa session and an exclusive cooking class, this immersive rainforest-and-island getaway is the perfect fit for those eager to escape the ordinary. Throughout, you'll experience a cleansing ceremony led by a local shaman, sail to and explore uninhabited islands, and photograph sea lion pups. In between, enjoy unique touches of luxury, including gourmet meals and a visit to the famous Papallacta Hot Springs.

Luxury digs and diverse wildlife await on Isla Isabela (photo courtesy of Golden Bay Galápagos)
Luxury digs and diverse wildlife await on Isla Isabela (photo courtesy of Golden Bay Galápagos)
Day Highlights Overnight
Day 1 Arrive in Quito, Exclusive Cooking Class Quito
Day 2 Transfer to Tena, Transfer to Minga Lodge & Rainforest Hike Tena
Day 3 Minga Bird-Watching & Agricultural Tour Tena
Day 4 Transfer to Quito, Visit Papallacta Hot Springs Quito
Day 5 Fly to Isla Santa Cruz, Visit Charles Darwin Research Station Isla Santa Cruz
Day 6 Galápagos Hidden Gems Boat Tour Isla Santa Cruz
Day 7 Fly to Isla San Cristóbal, Visit Tijeretas Hill Isla San Cristóbal
Day 8 Day Trip to Kicker Rock & Snorkeling Isla San Cristóbal
Day 9 Day Trip to Isla Española, Farewell Dinner Isla San Cristóbal
Day 10 Morning at Playa Mann, Fly to Quito, Depart   


Upon landing in Quito, indulge in a delightful stay at the 5-star EB by Eurobuilding and partake in an exquisite Ecuadorian cooking class. Then, meet up with a private driver the following morning who'll whisk you away to the Amazon city of Tena. Your accommodation here, the accessible-only-by-boat Minga Lodge & Reserve, provides the perfect base to learn about and interact with local Indigenous communities and embark on guided wildlife-watching hikes. Afterward, pause for a rejuvenating soak at the famous P​​apallacta Hot Springs before setting your sights on the Galápagos archipelago.

Your first destination in the Galápagos is the Finch Bay Galápagos Hotel on Isla Santa Cruz, and after settling in, you'll head to the Charles Darwin Research Center. A sailing trip to one of the nearby uninhabited islands lands on your itinerary next, which is followed up with a short flight to Isla San Cristóbal. Dedicate your first evening here to learning about conservation efforts, then take your newfound knowledge with you on a snorkeling trip to Kicker Rock and a cruise to Gardner Bay. Lastly, wake early to bask on the white sands of Playa Mann before catching your onward flight. Learn more

More Great 10-Day Galápagos Islands Itineraries

Looking for more inspiration for your trip to the Galápagos Islands? Check out these other 10-day Galápagos itineraries, with island-hopping cruises, land-based trips, and best-of tours to hit the highlights.

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Map of 10 Days in the Galápagos - 5 Luxury Itinerary Ideas
Map of 10 Days in the Galápagos - 5 Luxury Itinerary Ideas